How can Molecular Hydrogen improve fertility for Male and Female?

By: Sophia Ratilla 

Molecular hydrogen is one of the most plentiful substances in the universe, and it has been utilized for decades to produce hydrogen peroxide, which has a wide range of uses. Molecular hydrogen is essential for male and female fertility development.

It impacts metabolism, cellular energy generation, and metabolic processes that result in healthy pregnancies. By serving as an energy source for metabolic processes, hydrogen may affect our metabolism, aid glucose metabolism, and enhance cellular energy generation. 

The fetus and infants have an extremely high need for molecular hydrogen. According to research, a concentration of 0.1 percent in amniotic fluid is essential in embryonic development.

Furthermore, it influences glucose metabolism and cellular energy generation by functioning as a metabolic fuel that can be readily transferred throughout many tissues in the body, promoting metabolic processes that lead to healthy pregnancies.

For Male

Male fertility is determined by the intra-testicular testosterone concentration, which is generated by the Leydig cell in the testicular seminiferous tubules. Redox imbalance, caused by reactive oxygen species (ROS) and free radicals such as hydroxyl radical (OH) and peroxynitrite, has an impact on male fertility (ONOO-). 

These free radicals may also target DNA, lipids, and proteins, altering sperm structure and function and exacerbating the male fertility and spermatogenesis environment. To increase male fertility caused by this imbalance, H2 can play a role in regulating signals involved in testosterone hormone synthesis.

Protecting Sperm Cells 

Nutrition and supplements have been shown in studies to have a meaningful impact on preventing sperm damage. Vitamins and minerals, mainly, have been discovered to be critical for oxidative stress prevention.

As a result, antioxidant therapy may improve sperm parameters such as sperm count, motility, and morphology. Vegetables and fruits are the richest sources of natural antioxidants. We strongly advise you to eat various fruits and vegetables, including leafy greens, cruciferous vegetables, and tomatoes. With Biohackn’s molecular hydrogen generator you could have a week full of antioxidants in less than 15 minutes. This is because molecular hydrogen is one of the strongest antioxidant in the world - and we have managed to deliver strong concentrations of hydrogen in our generator.

Additionally, physical exercise is an essential source of oxidants. Exercising for 45 minutes three times a week has been demonstrated to reduce oxidative stress in seminal fluid. Additionally, we strongly advise you to engage in physical exercise. Therefore, limiting exposure to lifestyle variables such as smoking, alcohol intake, heat, radiation, and other contaminants is strongly encouraged. These enhance oxidative stress, which leads to sperm destruction and a decrease in fertility.

For Female

Molecular hydrogen treatment is increasingly being employed to slow down aging processes in several human body organs, particularly those involved in female fertility. 

Through further study, the effect of molecular hydrogen on LPS-induced astrocytic activation in vivo and in vitro. The number of activated astrocytes with hypertrophic shape increased in LPS-exposed offspring. This number was lower for the children of women who were administered molecular hydrogen.

LPS-induced pro-inflammatory cytokines were prevalent in primary cultured astrocytes when molecular hydrogen was present. In summary, the data suggest that maternal molecular hydrogen injection has neuroprotective effects and reduces the likelihood of neurodevelopmental impairments in kids later in life if maternal immune activation is generated.

For Pregnant Females 

While hydrogen water is probably part of your diet, being pregnant means it's time to reconsider what you're eating. You are no longer just concerned with your survival. Instead, you're looking after someone else. With this in mind, you may be asking what effects hydrogen water has on pregnancy.

When considering the hydrogen water adverse effects that molecular hydrogen can have on pregnancy, it is clear that hydrogen water is safe to consume while pregnant. With this in mind, knowing that your children can benefit from extra hydrogen makes our pouches the go-to nutritious beverage for pregnant women worldwide!

If pregnant, have our handy hydrogen water pouches on hand to satisfy your thirst. Your infant will undoubtedly appreciate it.

Pregnancy, Neonatal Development, and Newborns: Hydrogen in Reproductive Tissues

Healthy gametes (haploid cells) are required for successful reproduction. Following meiotic cell divisions in the testis and ovaries, gamete production occurs in the male and female gonads. Oxidative stress during gamete production is a possible concern that might lead to reproductive issues. Additionally, both sexes have tested hydrogen therapy to alleviate oxidative stress.

H2-enriched saline can protect rats and mice testis from oxidative damage caused by ischemia/reperfusion injury or nicotine-induced oxidative stress. Using H2-saline pretreatment in mice exposed to ionizing radiation reduced radiation damage in testicular tissue, including decreases in lipid peroxidation, proteins, and DNA damage. The number and quality of sperm increased following hydrogen treatment, which has been linked to minor oxidative damage. 

Sperm motility, which may be measured via Computer Assisted Sperm Analysis, is an essential determinant in male fertility (CAS). Hydrogen has been studied in vitro with trophoblast cell lines as a prospective treatment method for disorders during pregnancy.

Hydrogen administration to pregnant rats has been shown to benefit fetal rats' ischemia/reperfusion injury and hippocampus damage. Due to an elevated incidence of hypoxia or ischemia, newborns are at significant risk of excessive oxidative stress during delivery and the first preceding and post-partum months. Neurovascular dysfunction is observed quickly after delivery if there is any asphyxia. 

In treated rats, they were inhaling hydrogen gas soon after neonatal GMH decreased the prevalence of cerebral palsy and mental retardation. Premature delivery can also result in necrotizing enterocolitis (NEC, inflammation, and death of intestinal tissue), which increases mortality.


Hydrogen has numerous unique features that make it particularly beneficial for use in medicine and health, including robust and special antioxidant effects, gene regulatory abilities, quick rates of diffusion through tissue and cellular barriers, and an excellent safety record. 

Because of its systemic qualities and good penetration abilities, hydrogen can be beneficial in conditions of low blood flow and other scenarios that restrict the effectiveness of many different systemic therapies.

In a wide range of clinical disorders, hydrogen is beneficial in reducing signs and symptoms and improving quality of life. Because most of its benefits are frequently indirect, such as lowering excess oxidative stress, hydrogen is effective for many seemingly unrelated clinical diseases associated with redox imbalances. These disorders often lack specific therapies that remove the ailment. In such circumstances, hydrogen can be used with ineffective medicines to enhance clinical results.

The fact that hydrogen does not interfere with the underlying processes of most medicinal therapies is perhaps its most beneficial attribute. As a result, its benefit may be in adjuvant therapy in conjunction with established treatments for numerous clinical diseases.

The safety of hydrogen and the fact that no adverse effects have been reported are crucial considerations. This is especially important since many medications are restricted from usage due to toxicity, adverse effects, and undesirable dose-response characteristics. These issues do not apply to hydrogen.

Finally, the use of hydrogen for acute and chronic medical disorders is fast being surpassed by the use of hydrogen for female and male fertility health maintenance. These fields of hydrogen utilization will continue to expand and will eventually dwarf our society's current clinical applications of hydrogen.