Our vision for the world is to reverse chronic diseases that impact millions of life, such as Diabetes. We wish to see people reversing their Diabetes or better managing their blood sugar levels in the future. Hence we analyzed data from various diabetic journals and patients to see if altering the light in their environment could have a carry-over effect on Diabetes. We found that exposure to blue light has altered the way our bodies metabolize sugar or carbohydrates. Diabetes is a significant problem in the world.
Over 1 million people live with Diabetes in the U.A.E., with ages ranging anywhere between 20 -79 years old. According to our research and statistics by the International diabetes federation (I.D.F.), nearly 19 % of the U.A.E.'s population suffers from Diabetes. We then looked at data from IKEA's sleep survey to determine that 9 in 10 are not getting ideal sleep. When we look at the major contributing factors, technology, especially checking phones and emails, is the primary cause of lack of rest and sleep. So what do most of the technology have in common? It is - artificial high-energy blue light that suppresses Melatonin and harms individuals' health.
To investigate this co-relation further, We studied the function of Diabetes. Diabetes happens due to multiple interactions among a person's genetics, other environmental factors, and food choices. It would be challenging to control people's genetics and food choices. However, at Biohackn, we decided to take the third approach, which is controlling their environment. While we do not have complete control over people's environment, we decided to control the environmental light that passes through people's eyes as an ambitious company. Our research found that one-way Diabetes happens due to islet failure, which occurs as a result of losing Pancreatic B cell functioning. We have seen data that blue light at night in recent years alongside sleep loss and rotating shiftwork can increase susceptibility to Diabetes. As we expose ourselves to light at the wrong times of the day, our bodies can jump into a state of hyperglycemia ( high blood sugar levels), which is caused by islet failure.
Exposure to artificial light can also cause genetic mutations in CLOCK ( Circadian Locomotor output cycles protein kaput ), which can cause the proteins to become hyperglycemic, glucose intolerant, and lack proper insulin secretion, which can put one at high risk for Diabetes.
Exploring this further, we also found a connection between diabetes and vision problems caused by Diabetic Retinopathy (D.R.). Diabetic Retinopathy remains the leading vascular-associated cause of blindness throughout the world. We have seen data from the World health organization, which shows that Diabetic Retinopathy currently affects 150 million people worldwide, and this number is expected to reach 300 million by 2025.
We expect about 24 % of diabetic Retinopathy to occur in patients with Diabetes. Diabetic Retinopathy is a disease of the retina. One way to treat it is by intensive glycemic control ( blood sugar management), and the other is by using a laser photocoagulation laser process. However, we understand that both of these can be complicated and subjective to individuals. Therefore, we wanted to provide an alternative solution by managing pancreatic islet B cell activity by lowering the cells and tissues' activation in response to light modulation of the master-clock signals transferred from the brain. Furthermore, we also wanted to lessen the retina damage that comes with exposure to high-frequency blue light.