We designed Biohackn glasses to help people look good and help reduce the world obesity epidemic. According to the world health organization, obesity has tripled since the 1980s and has become an epidemic in many countries. Unfortunately, we see many children classified as overweight or obese and often lose out on all the benefits of playtime and physical activity with their friends. At Biohackn, we wanted to take this seriously as childhood obesity can result in a shorter lifespan, low confidence, low self-worth, and mental health issues like depression, anxiety, and loneliness. To help children and adults, we looked at chronobiology. We found out that circadian desynchrony, a disruption in the timing at which the body clocks, can induce obesity and metabolic dysfunction.
We looked at this issue, went back to the drawing board, and designed Biohackn glasses to target three prime areas correlated with obesity. These are chronodisruption, sleep deficiency, and melatonin suppression. At Oli, we believe that being overweight can endanger psychological, physiological, and cognitive performance. In addition, we are concerned about the rise of obesity-related disease and its effect on the global economy, resulting in healthcare costs, absenteeism from work, and damage to industries and economic productivity.
Constant exposure to the artificial blue light spectrum can hinder a person's weight loss journey. Weight loss is slowed via various pathways. One such pathway is via stimulation of a neuropeptide known as the "Alpha melanocyte-stimulating hormone "(a-MSH). A- M.S.H. regulates energy balance and how hungry someone gets via Ghrelin signaling (The hunger hormone). What does this mean? It merely means unprotected light exposure can play with hormones that make one hungry. As a result, people are always hungry, therefore overeating. We designed Oli to help block wavelengths, which wouldn't start a negative cascade of hormones.
Exposure to blue light at the wrong time only makes it worst. The command center of the brain, "Hypothalamus," contains receptors for hormones that either make us full and satiated (Leptin) or hungry and angry (Grehlin). Exposure to blue light has shown to change hormones' production, leaving us hungry and angry at the wrong times, resulting in weight gain. Some studies showed a dysregulation on the stomach clocks in animal models when they were exposed to light as less than 5 lux, which results in higher B.M.I. even if they eat the same amount of food. In human studies, a study conducted on almost 50,000 female nurses who sometimes operated at night shifts shows an increase in obesity rates due to higher exposure to artificial light at the wrong time of the day.
We see the most significant effect of this on shift workers whose work profile creates natural circadian disruption. For example, a study done on over 27,000 people showed that shift workers showed higher rates of obesity and triglycerides than non-shift workers.
One of the regulators for growth in the Body is called mTOR, or mammalian target of rapamycin. Its role is to regulate protein synthesis and make the Body grow while stopping the repair and recycling of damaged proteins. One reason plants and humans grow more in summer is the abundance of light shown to activate the mTOR pathway. Simultaneously, some growth is profitable, especially if one wants to grow muscles, but it comes at a cost. Stimulation of mTOR will down-regulate another pathway in the Body called AMPK or A.M.P.- 0 activated protein kinase, whose role is to recycle junk materials in the Body and repair it. Downregulation of AMPK is proven to decrease life span and increase cancer growth.
If one does not filter and block blue light at various times of the day, it can harm them by increasing new fat cells' production by signaling the Body to grow instead of relaxing. Also, exposure to blue light increases fasting glucose levels, putting people at risk of weight gain, and Type 2 diabetes.